Canine CTR&RAMP1 UM-UC-3
CBP71655
询 价
索取protocol
产品描述
产品数据库
| I. Background | |
| 犬CTR（降钙素受体）与RAMP1（受体活性修饰蛋白1）共表达时，主要形成对CGRP（降钙素基因相关肽）具有高亲和力的受体复合物，也被称为AMY1（胰淀素受体1亚型）。RAMP1是一种单次跨膜蛋白，它能改变CTR的配体识别特性，并协助其转运至细胞膜，是功能表达所必需的辅助亚基。该复合物在犬的血管平滑肌收缩等生理过程中发挥作用。 | |
| II. Description | |
| Canine CTR&RAMP1 UM-UC-3 细胞药靶模型很好的模拟了体内 CTR&RAMP1 的信号转导过程。 | |
| III. Introduction | |
| Host Cell: |
UM-UC-3 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: |
MEM+10%FBS+1% NEAA+ 1mM NaP+2μg/ml Puromycin+5μg/ml Blasticidin
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| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for Canine CTR&RAMP1 |
| Transducer: | Gs |
| IV. Representative Data | |
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